产品信息
抗原名称
Bcr-Abl
商品描述
DPH is a potent cell permeable c-Abl activator, which displays potent enzymatic and cellular activity in stimulating c-Abl activation.
分子量
336.32
纯度
98%
可溶性
DMSO : 100 mg/mL (297.34 mM; Need ultrasonic)
外观
white to tan powder
In vitro(体外研究)
DPH binds to the myristoyl binding site and prevents the formation of the bent conformation of the αI helix through steric hindrance, a mode of action distinct from the previously identified allosteric c-Abl inhibitor, GNF-2, that also binds to the myristoyl binding site. DPH represents the first cell-permeable, small-molecule tool compound for c-Abl activation.
背景
分子式
C18H13FN4O2
CAS号
484049-04-9
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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