产品信息
抗原名称
NF-κB；p65
商品描述
SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65.
分子量
565.67
纯度
>98%
可溶性
DMSO : 33 mg/mL (58.3 mM)
外观
white to beige powder
In vitro(体外研究)
SC75741 shows immunosuppressive activity by inhibiting human PBMC proliferation with IC50 of 2.2 μM. SC75741 inhibits replication of influenza A and B viruses by inhibiting NF-κB-mediated signalling on a transcriptional level. Moreover, SC75741 shows a high barrier for development of resistant virus variants.
In vivo(体内研究)
SC75741 (15 mg/kg i.p.) reduces virus replication and cytokine expression in mice lungs after H5N1 influenza virus infection.
背景
别名
SC 75741
分子式
C29H23N7O2S2
CAS号
913822-46-5
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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