PF-03550096 is a synthetic cannabinoid (CB) that selectively targets the peripheral CB₂ receptor over the central CB₁ receptor (K_is = 7.9 and 1,500 nM for human isoforms, respectively).^1,2 It shows similar selectivity for inhibiting forskolin-stimulated cAMP production in CHO cells expressing human CB₁ and CB₂ receptors (EC₅₀s = 450 and 2.1 nM, respectively).² PF-03550096 is orally bioavailable and significantly reduces colonic pain induced by 2,4,6-trinitrobenzene sulfonic acid in rats.² This product is intended for forensic and research applications.

≥98%