产品信息
抗原名称
MTH1
商品描述
TH 287 is a first-in-class MTH1 inhibitor (IC50 value 5.0 nM) that selectively and effectively kills U2OS and other cancer cell lines, with considerably less toxicity towards several primary or immortalized cells.
分子量
269.13
纯度
>98%
可溶性
DMSO 53 mg/mL (196.93 mM)
Ethanol 10 mg/mL warmed (37.15 mM)
Ethanol 10 mg/mL warmed (37.15 mM)
外观
Powder
In vitro(体外研究)
TH287 selectively and effectively kill U2OS and other cancer cell lines with less toxic to several primary or immortalized cells, and induces oxidative DNA damage.
In vivo(体内研究)
In C57Bl/6 mice, TH287 (5 mk/kg, i.p.) causes a peak time and maximum concentration of 0.5 h and 0.82μM.
背景
别名
TH287,TH-287
分子式
C11H10Cl2N4
CAS号
1609960-30-6
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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