产品信息
抗原名称
JNK3,JNK2
商品描述
TCS-JNK-5a is a selective inhibitor of JNK2 and JNK3 (pIC50 values are 6.7, 6.5, <5.0 and <4.8 for JNK3, JNK2, JNK1 and p38α respectively).
分子量
332.42
纯度
>98%
可溶性
DMSO : 33.2 mg/mL (100 mM)
外观
Powder
In vitro(体外研究)
JNK inhibitor IX significantly reduces caspase-3 activity by the inhibition of JNK activity in human dermal fibroblasts. JNK inhibition by JNK inhibitor IX significantly increases apoptotic death in response to imatinib mesylate (IM) by preventing c-ABL complete de-phosphorylation at Ser residues.
背景
别名
JNK Inhibitor IX；TCSJNK-5a
分子式
C20H16N2OS
CAS号
312917-14-9
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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