产品信息
商品描述
Labelled Isoniazid. Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).
分子量
141.16
可溶性
DMSO, Methanol
外观
White to Off-White Solid
背景
别名
4-(Pyridine-d4)carboxylic Acid Hydrazide; Isonicotinic Acid-d4 Hydrazide; 4-(Hydrazinocarbonyl)pyridine-d4; 4-(Pyridine-d4)carbonylhydrazine; 4-(Pyridine-d4)carboxylic Hydrazide; 4-(Pyridyl-d4)carbonylhydrazide; 5015 R.P.-d4; Armazid-d4; Armazide-d4; Atcotibine-d4; Isonizide-d4; Isotebezid-d4; Isozide-d4; Robisellin-d4; Sauterazid-d4; Zinadon-d4; Zonazide-d4; Tubazid-d4;
分子式
C6H3D4N3O
CAS号
774596-24-6
制备和贮存
保存方式
Refrigerator
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