产品信息
抗原名称
JAK1
商品描述
Solcitinib, also known as GSK2586184 or GLPG0778, is a Janus kinase 1 (JAK1) inhibitor.
分子量
389.45
纯度
＞98%
可溶性
DMSO : 20 mg/mL (51.35 mM; Need ultrasonic and warming)
外观
Powder
In vitro(体外研究)
Solcitinib is an orally active, competitive, potent, selective JAK1 inhibitor, with an IC50 of 9.8 nM, and 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively. Solcitinib is used in the research of moderate-to-severe plaque-type psoriasis.
背景
别名
索西替尼
分子式
C22H23N5O2
CAS号
1206163-45-2
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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