产品信息
抗原名称
LPL Receptor
商品描述
TY-52156 is a potent and selective S1P3 receptor antagonist with a Ki value of 110 nM.
分子量
364.27
纯度
98%
可溶性
DMSO : ≥ 100 mg/mL (274.52 mM)
In vitro(体外研究)
TY-52156 shows submicromolar potency and a high degree of selectivity for S1P3 receptor.
TY-52156 (10 μM; 10 min) inhibits S1P-induced p44/p42 MAPK phosphorylation.
TY-52156 (10 μM; 10 min) inhibits S1P-induced p44/p42 MAPK phosphorylation.
In vivo(体内研究)
TY-52156 (10 mg/kg, 30 mg/kg; p.o.) suppresses S1P3 receptor-induced bradycardia after oral administration in vivo.
背景
分子式
C18H19Cl2N3O
CAS号
934369-14-9
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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