产品信息
抗原名称
5-HT6
商品描述
SB-742457(RVT-101) is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects.
分子量
353.12
纯度
>98%
可溶性
DMSO：78 mg/mL (220.68 mM)
Ethanol：2 mg/mL (5.65 mM)
Ethanol：2 mg/mL (5.65 mM)
外观
Powder
In vitro(体外研究)
SB-742457 is a selective 5-HT6 receptor antagonist with cognition, memory, and learning-enhancing effects. SB-742457 is a novel cognitive enhancing agent for Alzheimer's disease. SB-742457 is a potential agent added to stablize donepezil treatment in subjects with mild-to-moderate Alzheimer's disease.
In vivo(体内研究)
SB-742457 is a potent and selective 5-HT6 receptor antagonist that is shown to reverse a scopolamine induced learning deficit in the novel object recognition test and to enhance performance in a water maze task by aged rats.
背景
别名
SB 742457，RVT 101，SB742457，RVT101
分子式
C19H19N3O2S
CAS号
607742-69-8
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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