5Z-6-2R-3S-3-4-氯-2-甲基苯基-磺酰基-氨基-甲基-双环-2-2-2-辛-2-基-5-己烯酸_216158-34-8_Absin
产品信息
商品描述
Prostaglandin E2 (PGE2) initiates its cellular effects by activating one of four E prostanoid (EP) receptors, EP1-4. ONO-8711 is a potent and selective competitive antagonist of the EP1 receptor (Ki = 0.6 and 1.7 nM for human and mouse EP1, respectively, versus 67 and 76 nM for mouse EP3 and human thromboxane receptor, respectively, and >1,000 nM for other receptors).1 ONO-8711 effectively reduces tumor incidence and multiplicity in mouse models of colon, breast, and oral cancer.1,2,3 It also suppresses pain and acid-induced HCO3- secretion in the stomach.4,5,6
分子量
439.2
纯度
≥98%
背景
分子式
C22H30ClNO4S
CAS号
216158-34-8
制备和贮存
保存方式
Store at -20℃
参考图片
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