产品信息
抗原名称
G-quadruplex
商品描述
Pyridostatin hydrochloride is a G-quadruplexe stabilizer, with a Kd of 490 nM.
分子量
778.94
纯度
98%
可溶性
H2O : 50 mg/mL (64.19 mM; Need ultrasonic)
In vitro(体外研究)
Pyridostatin hydrochloride is a G-quadruplexe stabilizer, with a Kd of 490 nM. Pyridostatin (PDS) shows neurotoxic activity against primary cortical neurons at 0.01-5 μM, causes DNA double-strand breaks (DSBs) at 1 μM, downregulates BRCA1 in neurons at 1, 2 or 5 μM. Pyridostatin interacts with G-quadruplex motifs in SRC and alters mRNA levels of damaged genes.
背景
分子式
C31H37Cl5N8O5
CAS号
1781882-65-2
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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