产品信息
抗原名称
LXR
商品描述
SR9243 is a new inhibitor of The nuclear receptor liver-X-receptor (LXR),inducing LXR-corepressor interaction.
分子量
626.62
纯度
>98%
可溶性
DMF 98 mg/mL warmed (156.39 mM)
DMSO <1 mg/mL
DMSO <1 mg/mL
外观
Powder
In vitro(体外研究)
In HEK293 cells expressing LXRs, SR9243 inhibits LXR activation by enhancing LXR-corepressor recruitment. In a variety of cancer cell types, SR9243 reduces cancer cell viability, induces apoptotic cell death, and sensitizes cancer cells to chemotherapeutic treatments.
In vivo(体内研究)
In Ob/Ob mice fed a high-fat diet, SR9243 (60 mg/kg, i.p.) inhibits LXR-dependent lipogenic enzyme gene expression and tumor growth.
背景
别名
SR 9243,SR9243,SR-9243
分子式
C31H32BrN04S2
CAS号
1613028-81-1
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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