产品信息
抗原名称
Casein Kinase
商品描述
LH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); displays no inhibitory activity at CK2.
分子量
316.81
纯度
>98%
可溶性
DMSO: ≥ 45 mg/mL
外观
Powder
In vitro(体外研究)
LH846 is a potent inhibitor of CKIδ, with an IC50 of 290 nM, less potently inhibits CKIα and CKIε, with IC50s of 2.5 μM and 1.3 μM, respectively, and has no effect on CK2. LH846 (3 or 10 μM) inhibits CKIδ-dependent phosphorylation of PER1 in HEK293T cells.
背景
别名
LH 846; LH-846
分子式
C16H13ClN2OS
CAS号
639052-78-1
制备和贮存
保存方式
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
参考图片
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