产品信息
商品描述
Icilin is a synthetic super-agonist of the transient receptor potential M8 (TRPM8) ion channel.
分子量
311.3
纯度
>97%
可溶性
DMSO : ≥ 54 mg/mL (173.47 mM)
外观
yellow solid
In vitro(体外研究)
Icilin-evoked TRPM8 currents show variable activation kinetics and Ca2+ dependence.Icilin-evoked currents exhibit highly variable latencies with pronounced desensitization.
In vivo(体内研究)
Icilin is a transient receptor potential cation channel subfamily M (TRPM8) agonist that produces behavioral activation in rats and mice. Icilin (3 mg/kg; s.c.) induces“Wet dog shake” in mice.
背景
分子式
C16H13N3O4
CAS号
36945-98-9
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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