产品信息
抗原名称
PHD2
商品描述
FG-2216 is a potent HIF-prolyl hydroxylase inhibitor with IC50 of 3.9 uM for PDH2 enzyme; orally bioavailable and induced significant and reversible Epo induction in vivo.
分子量
280.66
纯度
>98%
外观
Powder
In vitro(体外研究)
FG-2216 shows the ability to stabilize HIF-α to stimulate EPO secretion.
In vivo(体内研究)
In male rhesus macaques, FG-2216 (60 mg/kg, p.o.), induces significant and reversible Epo induction, and induces a small elevation of HbF expression.
背景
别名
FG2216,FG-2216,FG 2216
分子式
C12H9ClN2O4
CAS号
223387-75-5
制备和贮存
保存方式
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
参考图片
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