The metabolism of F series prostaglandins (PGs), including PGF_1α and PGF_2α, commonly begins with the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs. The removal of four carbons at the α-terminus and oxidation of the terminal ω carbon produces the abundant urinary metabolites, including tetranor-PGFM.^1,2,3,4 13,14-dihydro-15-keto tetranor PGF_1α is a potential metabolite of either PGF_1α or PGF_2α and likely precursor to tetranor-PGFM.

≥98%