产品信息
抗原名称
E1_E2_E3 Enzyme
商品描述
Skp2 inhibitor; thought to prevent assembly of Skp2-Skp1 complexes. Selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF complexes. Also inhibits Skp2-mediated p27 and Akt ubiquitination in vivo and in vitro. Suppresses the survival of cancer cells and cancer stem cells by triggering cell senescence and inhibiting glycolysis. Exhibits antitumor effects in multiple animal models and cancer cell lines.
分子量
420.52
纯度
98%
可溶性
1eq hydrochloride：20mM
DMSO：5 mM with gentle warming
DMSO：5 mM with gentle warming
背景
分子式
C24H24N2O3S
CAS号
222716-34-9
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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