产品信息
抗原名称
ROCK
商品描述
AR-13324是ROCK抑制剂，Ki值为0.2-10.3 nM。
分子量
526.45
纯度
≥98%
可溶性
DMSO ：20 mg/mL (37.99 mM)
外观
White to off white powder
In vitro(体外研究)
Previous study showed that at the cellular level, netarsudil had been shown to be able to induce loss of actin stress fibers, cell shape changes, loss of focal adhesions, as well as changes in extracellular matrix composition of TM cells.
In vivo(体内研究)
Animal efficacy study found that the topical treatment of netarsudil was able to affect both proximal (trabecular meshwork and Schlemm's Canal) and distal portions (intrascleral vessels) of the mouse conventional outflow tract.
背景
别名
奈他地尔
分子式
C28H29Cl2N3O3
CAS号
1253952-02-1
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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