产品信息
抗原名称
Bcl-xL
商品描述
A-1331852 is a high affinity BH3 mimetic Ligand of BCL protein BCL-XL.
分子量
658.81
纯度
>98%
可溶性
DMSO : ≥ 50 mg/mL (75.89 mM)
外观
Powder
In vitro(体外研究)
A-1331852 exhibits remarkable potency both as a single agent and in combination with TKIs in killing primary CD34+ CML cell. Also, It has remarkable potency in inducing apoptosis in these cells at lownanomolar concentrations as early as 1 h post-treatment.
In vivo(体内研究)
A-1331852 demonstrates antitumor efficacy in the Molt-4 xenograft model, inducing tumor regressions as a single agent.
背景
别名
A 1331852；A1331852
分子式
C38H38N6O3S
CAS号
1430844-80-6
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
本文来自投稿，不代表本人立场，如若转载，请注明出处：http://www.iamyjet.com/article/20377.html