产品信息
抗原名称
LARG
商品描述
Y16 is an inhibitor of G-protein–coupled Rho GEFs; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated signaling functions.
分子量
384.4272
纯度
98%
可溶性
DMSO : 25 mg/mL (65.03 mM; Need ultrasonic
外观
faint yellow to dark orange powder
In vitro(体外研究)
Y16 (10-30 μΜ; 24 hours; NIH 3T3 cells) could inhibit RhoA-GTP formation induced by serum dose dependently and is specific for RhoA[1]. Y16 (10-30 μΜ; 24 hours; NIH 3T3 cells) efficiently inhibits serum or SDF-1α-induced phospho-MLC and phospho-FAK formation, which are downstream of RhoA.
背景
别名
Y-16
分子式
C24H20N2O3
CAS号
429653-73-6
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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