L-Ascorbic acid (vitamin C) is essential for the synthesis of collagen, with deficiency resulting in scurvy.¹ Notably, humans and other primates, guinea pigs, and certain other animals lack an enzyme necessary for vitamin C synthesis.¹ L-Ascorbic acid 2-phosphate (AA2P) is a long-acting ascorbic acid derivative that stimulates collagen expression and formation and is used in human cell culture.^2,3 It may be included in media to enhance the survival of human embryonic stem cells or increase the growth and replicative lifespan of human corneal endothelial cells.^4,5 AA2P is also used to drive osteogenic differentiation in human adipose stem cells and in human mesenchymal stromal/stem cells.^6,7,8

≥95%