产品信息
抗原名称
HSET
商品描述
CW-069 is a novel and allosteric inhibitor of the microtubule motor protein HSET with IC50 value of 75 ± 20 μM; shows statistically significant selectivity over KSP.
分子量
500.33
纯度
>98%
可溶性
DMSO 100 mg/mL (199.86 mM)
Ethanol 4 mg/mL (7.99 mM)
Ethanol 4 mg/mL (7.99 mM)
外观
Powder
In vitro(体外研究)
CW069 increases multipolar spindles in N1E-115 cells with supernumerary centrosomes without altering bipolar spindle morphology in normal human dermal fibroblast cells. CW069 inhibits growth in cancer N1E-115 cells with IC50 of 10 μM, but not in NHDF or primary human bone marrow cells.
背景
别名
CW069; CW 069
分子式
C23H21IN2O3
CAS号
1594094-64-0
制备和贮存
保存方式
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
参考图片
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