产品信息
抗原名称
ALK2 ,ALK1
商品描述
ML347 is a selective BMP receptor inhibitor with IC50 of 32 nM for ALK2, >300-fold selectivity over ALK3. Also inhibits ALK1 activity with IC50 of 46 nM
分子量
352.39
纯度
>98%
可溶性
DMSO 10 mg/mL (28.37 mM)
外观
Powder
In vitro(体外研究)
ML347 also shows potency in BMP-responsive C2C12BRA cells with IC50 of 15 nM, and designated an MLPCN probe. ML347 displays high plasma protein binding in human, rat and mouse plasma.
背景
别名
ML 347; ML-347; LDN-193719; LDN193719; LDN 193719
分子式
C22 H16 N4 O
CAS号
1062368-49-3
制备和贮存
保存方式
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
参考图片
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