产品信息
抗原名称
GSK-3β
商品描述
The GSK3β Inhibitor XIX, IM-12 is a selective GSK-3β inhibitor with IC50 of 53 nM, and also enhances canonical Wnt signalling.
分子量
377.41
纯度
>98%
可溶性
Ethanol ：10 mg/mL (26.49 mM) warmed
DMSO ：70 mg/mL (185.5 mM)
DMSO ：70 mg/mL (185.5 mM)
外观
Powder
In vitro(体外研究)
In hNPCs, IM-12 inhibits GSK-3β activity with IC50 of 3.8 μM and subsequently increases β-catenin concentration significantly. Through the activation of canonical Wnt signalling pathway, IM-12 promotes the neuronal differentiation of human neural progenitor cells.
背景
别名
The GSK3β Inhibitor XIX, IM 12, IM-12,IM12
分子式
C22H20FN3O2
CAS号
1129669-05-1
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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