产品信息
抗原名称
ALK
商品描述
AP26113-analog (ALK-IN-1) is an analog of AP26113 which is a potent and selective ALK inhibitor. It is also an inhibitor of EGFR.
分子量
529.01
纯度
>98%
可溶性
Ethanol ：98 mg/mL (185.3 mM)
DMSO ：42 mg/mL (79.4 mM)
DMSO ：42 mg/mL (79.4 mM)
外观
Light yellow powder
In vitro(体外研究)
Brigatinib and AP26113-analog have similar potency against the triple-mutant EGFR with IC50 values of <100 nM. AP26113-analog suppresses phosphorylation of EGFR and its downstream signalling pathway in cells expressing all types of EGFR mutations.
背景
别名
布格替尼类似物
分子式
C26H34ClN6O2P
CAS号
1197958-12-5
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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