产品信息
抗原名称
JMJD2
商品描述
ML-324 is a JMJD2 histone demethylase inhibitor (JMJD2 IC50 = 920 nM)
分子量
349.43
纯度
>98%
可溶性
DMSO :43 mg/mL warmed (123.05 mM)
Ethanol :3 mg/mL warmed (8.58 mM)
Ethanol :3 mg/mL warmed (8.58 mM)
外观
Powder
In vitro(体外研究)
ML324 exhibits good Caco-2 cell permeability, and possesses excellent microsomal stability in the presence of both mouse and rat liver microsomes. ML324 demonstrates potent anti-viral activity against both herpes simplex virus (HSV) and human cytomegalovirus (hCMV) infection by inhibiting viral IE gene expression.
In vivo(体内研究)
In a mouse ganglia explant model of latently infected mice, ML324 suppresses the formation of HSV plaques, and blocks HSV-1 reactivation.
背景
别名
ML-324,ML324,ML 324
分子式
C21H23N3O2
CAS号
1222800-79-4
制备和贮存
保存方式
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
参考图片
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