产品信息
抗原名称
Interleukin Related
商品描述
Y-320 is a new phenylpyrazoleanilide immunomodulator.
分子量
505.01
纯度
>98%
可溶性
DMSO ：11 mg/mL (21.78 mM)
外观
Powder
In vitro(体外研究)
Y-320 also inhibits the production of IFN-γ and TNF-α by mouse CD4 T cells stimulated with IL-15, CXCL12, and anti-CD3 mAb.
In vivo(体内研究)
Y-320 (0.3-3 mg/kg p.o.) ameliorates collagen-induced arthritis (CIA) in Mice with a reduction of IL-17 mRNA in arthritic joints, and also shows therapeutic effects on CIA in cynomolgus monkeys. Moreover, Y-320 shows a synergistic effect in combination with anti-TNF-α mAb on chronic-progressing CIA in mice.
背景
分子式
C27H29ClN6O2
CAS号
288250-47-5
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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