产品信息
商品描述
Ertapenem sodium is a broad spectrum and long acting β-lactam antibiotic. Ertapenem sodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem sodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract.
分子量
498.51
纯度
>98%
可溶性
DMSO :100 mg/mL (201.0 mM)
Water :50 mg/mL (100.50 mM; Need ultrasonic)
Water :50 mg/mL (100.50 mM; Need ultrasonic)
外观
white to beige powder
In vitro(体外研究)
Ertapenem sodium (0-100 μg/mL approximately, 48 h) is active against 99.1% of all anaerobes with a mode MIC of 0.12 μg/mL and MIC90 of 1 μg/mL, and MIC’s ≥8 μg/mL for B.fragilis and B.vulgatus species, respectively.
In vivo(体内研究)
Ertapenem sodium (Subcutaneous injection, 0-10 mg/kg, 0-120 h after infection, S. aureus thigh tissue infection model) shows > 3 log10 CFU reduction of organism at 10 mg/kg, and maintains the activity with 3.3 and 4.4 log10 CFU eliminated at 2 mg/kg.
背景
别名
厄他培南钠;尔他培南钠
分子式
C22H25N3O7S.Na
CAS号
153773-82-1
制备和贮存
保存方式
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
参考图片
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