产品信息
抗原名称
KDM3A ,KDM4C ,KDM6B ,KDM2A ,KDM4E
商品描述
IOX1 is a potent and broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases.
分子量
189.17
纯度
>98%
可溶性
DMSO: 24 mg/mL
外观
Powder
In vitro(体外研究)
IOX1 increases H3K9me3 levels in HeLa cells via KDM4A inhibition without significant effect on cell viability. IOX1 shows lower efficacy in HeLa cells due to low cell permeability, while the n-octyl ester derivative improves its cell permeability.
背景
别名
IOX-1,IOX 1
分子式
C10H7NO3
CAS号
5852-78-8
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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