16-epi Latrunculin B, first isolated from the Red Sea sponge N. magnifica, is a stereoisomer of the actin polymerization inhibitor, latrunculin B (Item No. 10010631).^1,2 At 5-10 µg/ml, 16-epi latrunculin B can disrupt microfilament activity in an actin disruption assay.² It also demonstrates cytotoxic activity in mouse KA31T and NIH3T3 tumor cells (GI₅₀s = 1 and 4 µg/ml, respectively) and antiviral activity against herpes simplex type 1 virus (ED₅₀ = 1 µg/ml).¹

≥95%