产品信息
商品描述
Tacrine is an amino acridine compound that inhibits acetylcholinesterase (AChE), and has been proposed as a clinical treatment for Alzheimer’s disease.1 bis(7)-Tacrine is a tacrine dimer, linked via a 7-carbon alkyl spacer. It inhibits AChE with an IC50 of 0.40 nM, making it more than 1,000 times more potent than tacrine.2 bis(7)-Tacrine also protects against hydrogen peroxide induced apoptosis in rat pheochromocytoma cells.3
分子量
565.6
纯度
≥98%
背景
别名
1,7-N-heptylene-bis-9,9‘-amino-1,2,3,4-tetrahydro-acridine;
分子式
C33H40N4 • 2HCl
CAS号
224445-12-9
制备和贮存
保存方式
Store at -20℃
参考图片
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