产品信息
抗原名称
GABA uptake
商品描述
Tiagabine Hydrochloride is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. A selective <b>gamma-aminobutyric acid (GABA) reuptake</b> inhibitor.
分子量
412.01
纯度
98%
可溶性
DMSO ：41.2 mg/mL (100 mM)
water : 20.6 mg/mL (50 mM)
water : 20.6 mg/mL (50 mM)
外观
白色或类白色结晶性粉末
In vitro(体外研究)
Tiagabine is a potent inhibitor of GABA uptake into neurons and glial cells. It is involved in modulating GABA levels, especially in areas such as the hippocampus and thalamus. Tiagabine not only affected the decay kinetics of the IPSCs, it also reduced the frequency of occurrence of both spontaneous and miniature IPSCs.
In vivo(体内研究)
Tiagabine offers a significant neuroprotection in global ischemia in gerbils when given 30 min before ischemia but not when given 3 h after ischemia.
背景
别名
盐酸噻加宾；NO050328 hydrochloride；NO328 hydrochloride；TGB hydrochloride
分子式
C20H25NO2S2.HCl
CAS号
145821-59-6
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
本文来自投稿，不代表本人立场，如若转载，请注明出处：http://www.iamyjet.com/article/24786.html