产品信息
抗原名称
BiP/GRP78/HSPA5
商品描述
HA15 is a molecule that targets specifically <b>BiP/GRP78/HSPA5</b>. HA15 displays <b>anti-cancerous</b> activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
分子量
466.58
纯度
98%
可溶性
DMSO ：93 mg/mL (199.32 mM)
Ethanol ：45 mg/mL (96.45 mM)
Ethanol ：45 mg/mL (96.45 mM)
In vitro(体外研究)
HA15 induces ER stress leading to cancer cell death in vitro and overcomes BRAF inhibitor resistance in melanoma cells.
In vivo(体内研究)
HA15 induces ER stress leading to cancer cell death and exhibits strong efficacy in xenograft mouse models with melanoma cells either sensitive or resistant to BRAF inhibitors.
背景
别名
HA-15
分子式
C23H22N4O3S2
CAS号
1609402-14-3
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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