N-sup-2-sup-癸酰-L-精氨酰-L-缬氨酰-N-3S-6-亚氨基甲酰胺基-1-氯-2-氧代-3-己烷基-L-赖氨酰胺_150113-99-8_Absin
产品信息
商品描述
Furin is a proprotein convertase, converting precursor proteins to functional proteins within the Golgi/trans-Golgi secretory pathway. Furin inhibitor I is a selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases, including furin/SPC1 (Ki = ~1 nM), SPC2/PC2 (Ki = 0.36 nM), SPC3/PC1/PC3 (Ki = 2.0 nM), SPC4/PACE4 (Ki = 3.6 nM), SPC6/PC5/PC6, and SPC7/LPC/PC7/PC8 (Ki = 0.12 nM).1,2 Because furin activates viral glycoproteins, this inhibitor is a useful antiviral agent.3 In addition, it inhibits furin-dependent pro-MMP-2 activation in mononuclear inflammatory cells.4
分子量
744.4
纯度
≥95%
可溶性
DMF : 33 mg/ml
DMSO : 33 mg/ml
Ethanol : 33 mg/ml
PBS (pH 7.2) : 1 mg/ml
DMSO : 33 mg/ml
Ethanol : 33 mg/ml
PBS (pH 7.2) : 1 mg/ml
背景
分子式
C34H66ClN11O5
CAS号
150113-99-8
制备和贮存
保存方式
Store at -20℃，2 years
参考图片
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