1,3-Dibromo-2-propanol is a dihalogenated alcoholl that is reported as bifunctional crosslinking reagent. In other studies, it has been used to prepare the thioether ligand, used in the synthesis of palladium-phosphorus/sulfur nanoparticles. Also, it can be used in the preparation of 2-(alkoxy)propenyl bromide. Additionally, it is used in the synthesis of 1,3-propanediamine derivatives connected to carbohydrates (sugar-pendant diamines). Another use is in the chemical crosslinking of nine single substitution cysteine mutants of staphylococcal nuclease. Also, it can be used in the preparation of 1,3-dinitrooxy-2-propanol, via reaction with AgNO3 in MeCN at 80°C.

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