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BD Pharmingen- FITC Mouse Anti-Human CD61_BD Pharmingen

产品信息
荧光素标记
FITC
抗原名称
CD61 (Integrin β3)
宿主
Mouse IgG1, κ
简单描述
The VI-PL2 monoclonal antibody specifically binds to CD61. CD61 is a 105 kDa transmembrane glycoprotein that is also known as integrin β3 and platelet glycoprotein IIIa (GPIIIa or GP3A). It is expressed on platelets, megakaryocytes, osteoclasts and endothelia. Integrin β3 associates with gpIIa (CD41) to form the CD41/CD61 complex which mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the CD51/CD61 complex (vitronectin receptor). CD61 appears to bind to fibrinogen, fibronectin, vWF, vitronectin, and thrombospondin to mediate cell adhesion.
商品描述
VI-PL2 The VI-PL2 monoclonal antibody specifically binds to CD61. CD61 is a 105 kDa transmembrane glycoprotein that is also known as integrin β3 and platelet glycoprotein IIIa (GPIIIa or GP3A). It is expressed on platelets, megakaryocytes, osteoclasts and endothelia. Integrin β3 associates with gpIIa (CD41) to form the CD41/CD61 complex which mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the CD51/CD61 complex (vitronectin receptor). CD61 appears to bind to fibrinogen, fibronectin, vWF, vitronectin, and thrombospondin to mediate cell adhesion.
同种型
Mouse IgG1, κ
克隆号
克隆 VI-PL2 (also known as VIPL2) (RUO)
产品详情
FITC
Fluorescein (FITC) is part of the BD blue family of dyes. This is a small organic fluorochrome with an excitation maximum (Ex Max) at 494-nm and an emission maximum (Em Max) at 518-nm. FITC is designed to be excited by the Blue laser (488-nm) and detected using an optical filter centered near 520 nm (e.g., a 530/30-nm bandpass filter). Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
FITC
Blue 488 nm
494 nm
518 nm
应用
实验应用
Flow cytometry (Routinely Tested)
推荐用量
20 µl
反应种属
Human (QC Testing), Rhesus, Cynomolgus, Baboon, Dog, Cow (Tested in Development)
目标/特异性
CD61 (Integrin β3)
背景
别名
Integrin β3; Integrin beta-3; GP3A; GPIIIa; ITGB3; ITB3
制备和贮存
存储溶液
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
保存方式
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
文献
文献
研发参考(1) 1. Schlossman SF. Stuart F. Schlossman .. et al., ed. Leucocyte typing V : white cell differentiation antigens : proceedings of the fifth international workshop and conference held in Boston, USA, 3-7 November, 1993. Oxford: Oxford University Press; 1995.
数据库链接
Entrez-Gene ID
3690

参考图片

Flow cytometric analysis of CD61 expression on human peripheral blood platelets. Platelets were stained with either FITC Mouse Anti-Human CD61 (Cat. No. 555753/561913/557291; solid line histogram) or FITC Mouse IgG1, κ Isotype Control (Cat. No. 555748). Fluorescent histograms were derived from gated events with the side and forward light-scattering characteristics of viable platelets. Flow cytometry was performed on a BD FACScan™ system.

Flow cytometric analysis of CD61 expression on human peripheral blood platelets. Platelets were stained with either FITC Mouse Anti-Human CD61 (Cat. No. 555753/561913/557291; solid line histogram) or FITC Mouse IgG1, κ Isotype Control (Cat. No. 555748). Fluorescent histograms were derived from gated events with the side and forward light-scattering characteristics of viable platelets. Flow cytometry was performed on a BD FACScan™ system.

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