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BD Pharmingen- APC Mouse Anti-Human CD18_BD Pharmingen

艾美捷科技 • 2025年08月20日 08:41:50 • 抗体 • 阅读 43 • 标签
产品信息
荧光素标记
APC
抗原名称
CD18 (Integrin β2)
宿主
Mouse BALB/c IgG1, κ
免疫原
Cloned Human DS6 TCR γδ+ Cells
简单描述
The 6.7 monoclonal antibody specifically binds to β2 integrin, a 90-95 kDa transmembrane protein, which associates non-covalently as a heterodimer with the a chains of CD11a, CD11b, or CD11c. CD18 is expressed on lymphocytes, monocytes, and more weakly on granulocytes. LFA-1 has been shown to play an important role in homotypic and heterotypic cellular adhesion in immune and inflammatory responses.
商品描述
6.7 The 6.7 monoclonal antibody specifically binds to β2 integrin, a 90-95 kDa transmembrane protein, which associates non-covalently as a heterodimer with the a chains of CD11a, CD11b, or CD11c. CD18 is expressed on lymphocytes, monocytes, and more weakly on granulocytes. LFA-1 has been shown to play an important role in homotypic and heterotypic cellular adhesion in immune and inflammatory responses.
同种型
Mouse BALB/c IgG1, κ
克隆号
克隆 6.7 (RUO)
产品详情
APC
Allophycocyanin (APC), is part of the BD family of phycobiliprotein dyes. This fluorochrome is a multimeric fluorescent phycobiliprotein with excitation maximum (Ex Max) of 651 nm and an emission maximum (Em Max) at 660 nm. APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
APC
Red 627-640 nm
651 nm
660 nm
应用
实验应用
Flow cytometry (Routinely Tested)
推荐用量
20 µl
反应种属
Human (QC Testing), Rhesus, Cynomolgus, Pig, Rabbit (Tested in Development)
目标/特异性
CD18 (Integrin β2)
背景
别名
ITGB2; Integrin beta-2; Beta subunit for LFA-1, MAC-1/CR3, and p150,95
制备和贮存
存储溶液
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
保存方式
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
文献
文献
研发参考(2) 1. Barclay NA, Brown MH, Birkeland ML, et al, ed. The Leukocyte Antigen FactsBook. San Diego, CA: Academic Press; 1997. 2. Schlossman SF. Stuart F. Schlossman .. et al., ed. Leucocyte typing V : white cell differentiation antigens : proceedings of the fifth international workshop and conference held in Boston, USA, 3-7 November, 1993. Oxford: Oxford University Press; 1995.
数据库链接
Entrez-Gene ID
3689

参考图片

Flow cytometric analysis of expression of CD18 on peripheral blood lymphocytes. Whole blood was stained with APC Mouse Anti-Human CD18 (Cat. No. 551060; solid line histogram) or with an APC Mouse IgG1, κ Isotype Control (Cat. No. 555751; dashed line histogram). The erythrocytes were lysed with Lysing Buffer (Cat. No. 555899). The fluorescence histograms were derived from gated events with the forward and side light-scattering characteristics of viable lymphocytes.

Flow cytometric analysis of expression of CD18 on peripheral blood lymphocytes. Whole blood was stained with APC Mouse Anti-Human CD18 (Cat. No. 551060; solid line histogram) or with an APC Mouse IgG1, κ Isotype Control (Cat. No. 555751; dashed line histogram). The erythrocytes were lysed with Lysing Buffer (Cat. No. 555899). The fluorescence histograms were derived from gated events with the forward and side light-scattering characteristics of viable lymphocytes.

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