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BD Pharmingen- Purified Mouse Anti-MLH-1 with Control_BD Pharmingen

艾美捷科技 • 2025年08月20日 08:57:03 • 抗体 • 阅读 12 • 标签
产品信息
抗原名称
MLH-1
克隆号
G168-15
BD化合物表
  • 描述
    数量/尺寸
    零件号
    EntrezGene ID
  • Purified Mouse Anti-Human MLH-1
    50 µg (3 ea)
    51-1327GR
    N/A
  • Jurkat Cell Lysate
    50 µg (1 ea)
    51-16526N
    N/A
应用
实验应用
Western blot (Routinely Tested), Immunohistochemistry-frozen, Immunohistochemistry-paraffin (Tested During Development)
反应种属
Human (QC Testing)
目标/特异性
MLH-1
文献
文献
研发参考(8) 1. Baker SM, Plug AW, Prolla TA. Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over. Nat Genet. 1996; 13(3):336-342. (Immunogen: Western blot). 2. Cleaver JE. It was a very good year for DNA repair. Cell. 1994; 76(1):1-4. (Biology). 3. Fishel R, Ewel A, Lee S, Lescoe MK, Griffith J. Binding of mismatched microsatellite DNA sequences by the human MSH2 protein. Science. 1994; 266(5189):1403-1405. (Biology). 4. Li GM, Modrich P. Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs. Proc Natl Acad Sci U S A. 1995; 92(6):1950-1954. (Biology). 5. Prolla TA, Christie DM, Liskay RM. Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene. Mol Cell Biol. 1994; 14(1):407-415. (Biology). 6. Prolla TA, Pang Q, Alani E, Kolodner RD, Liskay RM. MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. Science. 1994; 265(5175):1091-1093. (Biology). 7. Su SS, Modrich P. Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs. Proc Natl Acad Sci U S A. 1986; 83(14):5057-5061. (Biology). 8. Wilson TM, Ewel A, Duguid JR. Differential cellular expression of the human MSH2 repair enzyme in small and large intestine. Cancer Res. 1995; 55(22):5146-5150. (Biology).

参考图片

Western blot analysis of MLH1. Lysate from Jurkat cells were probed with anti-MLH1 (clone G168-15, Comp. No. 51-1327GR) at concentrations of 2.0 (lane 1), 1.0 (lane 2), and 0.5 µg/ml (lane 3). MLH1 is identified as a band between 80-85 kDa.

Immunohistochemiical staining: Acetone-fixed, frozen tissue section of human colon carcinoma stained for MLH1 (clone G168-15, Cat. No. 550838) using a DAB chromogen and Hematoxylin counterstain. Cells expressing MLH-1 can be identifed by the intense brown labeling of their cell nuclei.

Western blot analysis of MLH1. Lysate from Jurkat cells were probed with anti-MLH1 (clone G168-15, Comp. No. 51-1327GR) at concentrations of 2.0 (lane 1), 1.0 (lane 2), and 0.5 µg/ml (lane 3). MLH1 is identified as a band between 80-85 kDa.

Immunohistochemiical staining: Acetone-fixed, frozen tissue section of human colon carcinoma stained for MLH1 (clone G168-15, Cat. No. 550838) using a DAB chromogen and Hematoxylin counterstain. Cells expressing MLH-1 can be identifed by the intense brown labeling of their cell nuclei.

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