Exposure to a test substance can result in damage to the chromosomes or spindle apparatus of cells. During routine cell division, this type of damage can create a smaller 'micro'-nucleus, apart from the main nucleus. When red blood cells mature the main nucleus is expelled. Micronuclei remain behind and can easily be seen in a cell with no other DNA. This makes red blood cells ideal for measuring this endpoint. In Vivo MicroFlow kits use flow cytometry to quickly and reproducibly measure micronuclei. Each MicroFlow PLUS-M kit contains all of the quality-assured supplies & reagents to collect and fix 60 mouse blood samples. With this MicroFlow PLUS kit, analyses are performed using your own in-house flow cytometer.

Rat (QC Testing)