BD Pharmingen- Biotin Mouse Anti-Mouse IgM-b_BD Pharmingen
产品信息
抗原名称
IgM[b]
宿主
Mouse BALB/c IgG1, κ
免疫原
C57BL/10 mouse splenocytes
简单描述
The AF6-78 antibody reacts specifically with mouse IgM of
Igh-C[b]
and related haplotypes (e.g., C57BL/6, C57BL/10, SJL, AKR, NZB). It does not react with IgM of
Igh-C[a]
or related haplotypes (e.g., BALB/c, C58, CBA, C3H/Bi, C3H/He, DBA/1, DBA/2, PL, RIII). Cross-reaction with IgM of
Igh-C[e]
haplotype (e.g., A/J) has been observed. AF6-78 antibody does not react with free µ heavy chain in vitro or in the cytoplasm of pre-B lymphocytes, which lack Ig light chain. It has not been shown to stimulate B-cell proliferation.
商品描述
AF6-78
The AF6-78 antibody reacts specifically with mouse IgM of
Igh-C[b]
and related haplotypes (e.g., C57BL/6, C57BL/10, SJL, AKR, NZB). It does not react with IgM of
Igh-C[a]
or related haplotypes (e.g., BALB/c, C58, CBA, C3H/Bi, C3H/He, DBA/1, DBA/2, PL, RIII). Cross-reaction with IgM of
Igh-C[e]
haplotype (e.g., A/J) has been observed. AF6-78 antibody does not react with free µ heavy chain in vitro or in the cytoplasm of pre-B lymphocytes, which lack Ig light chain. It has not been shown to stimulate B-cell proliferation.
同种型
Mouse BALB/c IgG1, κ
克隆号
克隆 AF6-78 (RUO)
浓度
0.5 mg/ml
产品详情
Biotin
Biotin is a ubiquitous co-factor (also known as Vitamin B7) that has many properties that make it extremely useful for molecular biology. Biotin has an extremely high affinity for the Avidin family of proteins (Kd = 10-15 M), making it the perfect tool to link two molecules. Biotin labeled antibodies can be combined with any number of Avidin-conjugated probes in order to customize an assay to a particular need. This is especially useful in the case of magnetic cell separation using streptavidin/magnetic bead conjugates, or in the case of flow cytometry using streptavidin/fluorophore conjugates.
应用
实验应用
ELISA (Routinely Tested), Flow cytometry (Tested During Development)
反应种属
Mouse (QC Testing)
目标/特异性
IgM[b]
背景
别名
Igh-6b
制备和贮存
存储溶液
Aqueous buffered solution containing ≤0.09% sodium azide.
保存方式
Aqueous buffered solution containing ≤0.09% sodium azide.
文献
文献
研发参考(2)
1. Stall AM, Loken MR. Allotypic specificities of murine IgD and IgM recognized by monoclonal antibodies. J Immunol. 1984; 132(2):787-795. (Immunogen).
2. Stall AM. Mouse immunoglobulin allotypes. In: Herzenberg LA, Weir DM, Blackwell C, ed. Weir's Handbook of Experimental Immunology. Blackwell Science Publishers; 1996:27.1-27.16.
参考图片
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