I-A/I-E

Rat DA, also known as DA/HA IgG2a, κ

BALB/c mouse epidermal Langerhans cells

The 2G9 monoclonal antibody reacts with the I-Ad and I-Ed MHC class II alloantigens.  It also reacts with transfectants expressing I-Eb and I-Ek and with cells from mice of the H-2p and H-2q haplotypes.  This antibody is non-reactive with cells from SJL (H-2s) and NOD (H-2g7) mice.  Flow cytometric analysis indicates that the 2G9 and M5/114.15.2 monoclonal antibodies have comparable reactivity on cells from mice with I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek alloantigens.

2G9 The 2G9 monoclonal antibody reacts with the I-Ad and I-Ed MHC class II alloantigens.  It also reacts with transfectants expressing I-Eb and I-Ek and with cells from mice of the H-2p and H-2q haplotypes.  This antibody is non-reactive with cells from SJL (H-2s) and NOD (H-2g7) mice.  Flow cytometric analysis indicates that the 2G9 and M5/114.15.2 monoclonal antibodies have comparable reactivity on cells from mice with I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek alloantigens.

Rat DA, also known as DA/HA IgG2a, κ

克隆 2G9 (RUO)

0.5 mg/ml

Flow cytometry (Routinely Tested), Immunoprecipitation, Intracellular staining (flow cytometry) (Reported)

Mouse (QC Testing)

I-A/I-E

H-2I; I-Ad, -Ed; I-Eb and I-Ek MHC class II alloantigens; Ia Ag; MHC II

Aqueous buffered solution containing ≤0.09% sodium azide.

研发参考(1) 1. Becker D, Mohamadzadeh M, Reske K, Knop J. Increased level of intracellular MHC class II molecules in murine Langerhans cells following in vivo and in vitro administration of contact allergens. J Invest Dermatol. 1992; 99(5):545-549. (Immunogen: Immunofluorescence, Immunoprecipitation).

14961, 14969