产品信息
抗原名称
G9a
商品描述
BIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM.
分子量
490.64
纯度
＞98%
可溶性
H2O : 14.29 mg/mL (29.13 mM; Need ultrasonic)
外观
Off-white solid
In vitro(体外研究)
BIX-01294 (4.1 μM) treatment of G9anull ES cells results in a further reduction in H3K9me2 levels. BIX-01294 reduces H3K9me2 at several G9a target genes. BIX-01294 (5 µM) reduces levels of global H3K9 methylation in pronuclear- and 2-cell-stage embryos. Embryos transiently exposed to BIX-01294 have a reduced ability to establish pregnancy. BIX-01294 (1 µg/mL) causes reduction in the BrdU incorporation of fetal PASMCs. BIX-01294 treatment decreases the PASMCs migration induced by PDGF.
背景
别名
BIX 01294; BIX01294,BIX-01294
分子式
C28H38N6O2
CAS号
935693-62-2
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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