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AZD-5069_878385-84-3_Absin

产品信息
抗原名称
CXCR
商品描述

AZD-5069 is a potent and selective CXCR2 antagonist with the potential to inhibit neutrophil migration into the airways in patients with COPD.

分子量
476.51
纯度

>98%

可溶性
DMSO : 90 mg/mL (188.87 mM; Need ultrasonic)
外观
White to off-white powder
In vitro(体外研究)
AZD-5069 (Compound 2) acts as CXCR2 antagonist by inhibition of -IL-8 binding to human CXCR2 receptors and as inhibitor of GROα-induced Ca2+ flux in human neutrophils loaded with fluo-3 dye.
背景
别名
AZD 5069;AZD5069
分子式
C18H22F2N4O5S2
CAS号
878385-84-3
制备和贮存
保存方式
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

参考图片

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