产品信息
抗原名称
TrkA
商品描述
GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM; little activity to c-Raf1 and CDK2.
分子量
275.3
纯度
>98%
可溶性
DMSO : 4.1 mg/mL (15 mM)
外观
orange Powder
In vitro(体外研究)
GW441756 can specifically block TrkA-induced cell death in a dose-dependent manner. GW441756 can block TrkA-mediated γH2AX production and apoptosis in TrkA-overexpressing cells.
背景
别名
GW 441756; GW-441756
分子式
C17H13N3O
CAS号
504433-23-2
制备和贮存
保存方式
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
参考图片
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