产品信息
商品描述
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 µM. (±)13(14)-EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models. (±)13(14)-EpDPA and other epoxy metabolites of DHA are also reported to potently inhibit angiogenesis and tumor growth in in vitro assays.
分子量
344.5
纯度
≥95%
可溶性
DMF : 25 mg/mL
DMSO : 20 mg/mL
Ethanol : 50 mg/mL
DMSO : 20 mg/mL
Ethanol : 50 mg/mL
外观
solution in ethanol
背景
别名
(±)13,14-EDP；(±)13,14-EpDPE；(±)13,14-epoxy DPA；(±)13,14-epoxy Docosapentaenoic Acid
分子式
C22H32O3
CAS号
895127-64-7
制备和贮存
保存方式
Store at -20℃，1 year
参考图片
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