产品信息
商品描述
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 µM. (±)10(11)-EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in inflammatory and neuropathic pain models and to potently inhibit angiogenesis and tumor growth in in vitro assays.
分子量
344.5
纯度
≥95%
可溶性
DMF : 25 mg/mL
DMSO : 20 mg/mL
Ethanol : 50 mg/mL
DMSO : 20 mg/mL
Ethanol : 50 mg/mL
外观
solution in ethanol
背景
别名
(±)10,11-EDP；(±)10,11-EpDPE；(±)10,11-epoxy DPA；(±)10,11-epoxy Docosapentaenoic Acid
分子式
C22H32O3
CAS号
895127-65-8
制备和贮存
保存方式
Store at -20℃，1 year.
参考图片
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