产品信息
抗原名称
G9a
商品描述
BRD4770 is a selective inhibitor of the histone methyltransferase G9a.
分子量
413.47
纯度
>98%
可溶性
DMSO 27 mg/mL warmed (65.3 mM)
外观
Powder
In vitro(体外研究)
BRD4770 reduces cellular levels of di- and trimethylated H3K9 via inhibition of G9a, induces senescence, and inhibits both anchorage-dependent and -independent proliferation in the pancreatic cancer cell line PANC-1. The combination of gossypol and BRD4770 increases LC3-II levels and the autophagosome number, and thus acts in synergy to induce cell death in PANC-1 cells.
背景
别名
BRD-4770, BRD 4770
分子式
C25H23N3O3
CAS号
1374601-40-7
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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