产品信息
抗原名称
Thyroid Hormone Receptor
商品描述
Protirelin is a tripeptide that stimulates the release of thyrotropin and prolactin.
分子量
362.38
纯度
98%
可溶性
DMSO : 67 mg/mL (184.9 mM)
Ethanol : 67 mg/mL (184.9 mM)
Water : 66 mg/mL (182.1 mM)
Ethanol : 67 mg/mL (184.9 mM)
Water : 66 mg/mL (182.1 mM)
外观
粉末
In vivo(体内研究)
Protirelin (TRH) is an evolutionarily ancient neuropeptide, having its origin before the divergence of protostomes and deuterostomes, and may ancestrally have been involved in the control of postembryonic growth and reproduction. The effect of the thyrotropin-releasing hormone (Protirelin, TRH), one of the hypothalamic releasing hormones, on body temperature is investigated in the rat. Protirelin, in doses of 1, 5, 10 and 20 mg/kg, is injected intraperitoneally to male Wistar rats weighing 200-250 g. Protirelin causes a temporary rise in body temperature dose-dependently. The thyroidectomized rats injected 20 mg/kg of Protirelin which induces a significant hyperthermia in the sham-operated animals, fail to show a rise in body temperature. The present results suggest that a release of thyroid hormone might participate in the hyperthermic action of Protirelin.
背景
别名
普罗瑞林；TRH；TRF；TRH；TSH-RF；pGlu-His-Pro-NH2
分子式
C16H22N6O4
CAS号
24305-27-9
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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