BD Pharmingen- Purified Mouse Anti-Human CD14_BD Pharmingen
产品信息
抗原名称
CD14
宿主
Mouse IgG2a, κ
免疫原
Human CD14 Protein
简单描述
The M5E2 monoclonal antibody specifically binds to CD14, a 53–55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB.
商品描述
M5E2
The M5E2 monoclonal antibody specifically binds to CD14, a 53–55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB.
同种型
Mouse IgG2a, κ
克隆号
克隆 M5E2 (RUO)
浓度
250 µg/ml
产品详情
Purified
Tissue culture supernatant is purified by either protein A/G or affinity purification methods. Both methods yield antibody in solution that is free of most other soluble proteins, lipids, etc. This format provides pure antibody that is suitable for a number of downstream applications including: secondary labeling for flow cytometry or microscopy, ELISA, Western blot, etc.
应用
实验应用
Flow cytometry (Routinely Tested), Immunohistochemistry-frozen, Immunohistochemistry-zinc-fixed (Tested During Development)
反应种属
Human (QC Testing), Rhesus,Cynomolgus,Dog (Tested in Development)
目标/特异性
CD14
背景
别名
LPS receptor; LPS-R; Myeloid cell-specific leucine-rich glycoprotein
制备和贮存
存储溶液
Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
保存方式
Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
参考图片
Immunohistochemical staining of CD14 positive cells. Frozen sections of normal human tonsil was reacted with the M5E2 antibody. Macrophages and reticular dendritic cells positive for CD14 can be identified by the intense brown labeling of their cell membranes. Amplification 40X.
Immunohistochemical staining of CD14 positive cells. Frozen sections of normal human tonsil was reacted with the M5E2 antibody. Macrophages and reticular dendritic cells positive for CD14 can be identified by the intense brown labeling of their cell membranes. Amplification 40X.
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