产品信息
简单描述
Interferon-γ inducible protein-10 (IP-10) is a 10 kD protein that belongs to CXC chemokine family. Unlike other CXC chemokines, IP-10 is a chemoattractant for activated lymphocytes, but not resting lymphocytes or neutrophils. The gene for human IP-10 has been mapped to chromosome 4q2. CXC chemokine receptor 3 (CXCR3) has been identified as the receptor for IP-10.
Purity: The recombinant human IP-10 was produced and found to be ≥ 95% pure by SDS-PAGE analysis and visualized by silver strain.
克隆号
(RUO)
应用
目标/特异性
IP-10
制备和贮存
存储溶液
Lyophilized in an aqueous buffered solution containing BSA.
文献
文献
Development References(4)
1. Farber JM. Mig and IP-10: CXC chemokines that target lymphocytes. J Leukoc Biol. 1997; 61(3):246-257. (Biology).
2. Loetscher M, Gerber B, Loetscher P, et al. Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med. 1996; 184(3):963-969. (Biology).
3. Luster AD, Jhanwar SC, Chaganti RS, Kersey JH, Ravetch JV. Interferon-inducible gene maps to a chromosomal band associated with a (4;11) translocation in acute leukemia cells. Proc Natl Acad Sci U S A. 1987; 84(9):2868-2871. (Biology).
4. Luster AD, Ravetch JV. Biochemical characterization of a gamma interferon-inducible cytokine (IP-10). J Exp Med. 1987; 166(4):1084-1097. (Biology).
参考图片
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